AJTR Copyright © 2009-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711
Volume 9, Number 2:197-822;2017
American Journal of Translational Research


Hong Zhao, Yelda C Orhan, Xiaoming Zha, Ecem Esencan, Robert T Chatterton, Serdar E Bulun: AMP-activated protein kinase and energy balance in breast cancer. Am J Transl Res 2017;9(2):197-213. (Abstract AJTR0038853, Full text, PDF).

Kuan-Hung Chen, Chih-Hung Chen, Christopher Glenn Wallace, Yen-Ta Chen, Chih-Chao Yang, Pei-Hsun Sung, Hsin-Ju Chiang, Yi-Ling Chen, Sarah Chua, Hon-Kan Yip, Jiin-Tsuey Cheng: Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome. Am J Transl Res 2017;9(2):214-229. (Abstract AJTR0037042, Full text, PDF).

Dongmei Fan, Xiaojuan Xie, Pengwei Qi, Xianan Yang, Ximeng Jin: Human mesenchymal stem cell homing induced by SKOV3 cells. Am J Transl Res 2017;9(2):230-246. (Abstract AJTR0020174, Full text, PDF).

Liqin Qi, Zhou Chen, Yanping Wang, Xiaoying Liu, Xiaohong Liu, Linfang Ke, Zhongjie Zheng, Xiaowei Lin, Yu Zhou, Lijuan Wu, Libin Liu: Subcutaneous liraglutide ameliorates methylglyoxal-induced Alzheimer-like tau pathology and cognitive impairment by modulating tau hyperphosphorylation and glycogen synthase kinase-3β. Am J Transl Res 2017;9(2):247-260. (Abstract AJTR0036499, Full text, PDF).

Marisol Maya-López, Ana Laura Colín-González, Gabriela Aguilera, María Eduarda de Lima, Ana Colpo-Ceolin, Edgar Rangel-López, Juana Villeda-Hernández, Daniel Rembao-Bojórquez, Isaac Túnez, Armando Luna-López, Roberto Lazzarini-Lechuga, Viridiana Yazmín González-Puertos, Pedro Posadas-Rodríguez, Alejandro Silva-Palacios, Mina Königsberg, Abel Santamaría: Neuroprotective effect of WIN55,212-2 against 3-nitropropionic acid-induced toxicity in the rat brain: involvement of CB1 and NMDA receptors. Am J Transl Res 2017;9(2):261-274. (Abstract AJTR0042538, Full text, PDF).

Zhenlang Lin, Yingying Hu, Zhouguang Wang, Shulin Pan, Hao Zhang, Libing Ye, Hongyu Zhang, Mingchu Fang, Huai Jiang, Junming Ye, Jian Xiao, Li Liu: Intranasal basic fibroblast growth factor attenuates endoplasmic reticulum stress and brain injury in neonatal hypoxic-ischaemic injury. Am J Transl Res 2017;9(2):275-288. (Abstract AJTR0041180, Full text, PDF).

Tian Wu, Yuanyuan Xiang, Yu Lv, Dai Li, Lijin Yu, Ren Guo: miR-590-3p mediates the protective effect of curcumin on injured endothelial cells induced by angiotensin II. Am J Transl Res 2017;9(2):289-300. (Abstract AJTR0039018, Full text, PDF).

Chang Jun Liu, Jin Hui Yang, Fei Zhou Huang, Wan Pin Nie, Chu Ping Liu, Xian Hai Mao, Xin Min Yin, Xian Bo Shen, Chuang Peng, Mei Fu Chen, Bo Jiang, Xun Yang Liu, Jin Shu Wu: Glutathione-s-transferase A 4 (GSTA4) suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting AKT pathway. Am J Transl Res 2017;9(2):301-315. (Abstract AJTR0040717, Full text, PDF).

Feng Ding, Jing Wang, Guoxiong Zhu, Huaqiang Zhao, Gaoyi Wu, Lei Chen: Osteopontin stimulates matrix metalloproteinase expression through the nuclear factor-κB signaling pathway in rat temporomandibular joint and condylar chondrocytes. Am J Transl Res 2017;9(2):316-329. (Abstract AJTR0032229, Full text,
PDF).

Xiang-Fang Chen, Wei Tang, Wei-Dong Lin, Zi-Yu Liu, Xiao-Xiao Lu, Bei Zhang, Fei Ye, Zhi-Min Liu, Jun-Jie Zou, Wan-Qing Liao: Receptor for advanced glycation end as drug targets in diabetes-induced skin lesion. Am J Transl Res 2017;9(2):330-342. (Abstract AJTR0039993, Full text, PDF).

Gui-Jun Wang, Lian-Yi Guo, Hong-Xin Wang, Yu-Sheng Yao: IP3R and RyR calcium channels are involved in neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α. Am J Transl Res 2017;9(2):343-354. (Abstract AJTR0039550, Full text, PDF).

Ying-Hui Zhang, Li-Zhi Wu, Hong-Lu Liang, Yang Yang, Jie Qiu, Qing Kan, Wen Zhu, Cheng-Ling Ma, Xiao-Yu Zhou: Pulmonary surfactant synthesis in miRNA-26a-1/miRNA-26a-2 double knockout mice generated using the CRISPR/Cas9 system. Am J Transl Res 2017;9(2):355-365. (Abstract AJTR0040400, Full text, PDF).

Shilong Zhang, Xinxin Dong, Tongyu Ji, Guoxiao Chen, Lei Shan: Long non-coding RNA UCA1 promotes cell progression by acting as a competing endogenous RNA of ATF2 in prostate cancer. Am J Transl Res 2017;9(2):366-375. (Abstract AJTR0043367, Full text, PDF).

Bo Yang, Liang Xiao, Sheng Liu, Xiaoyu Liu, Yan Luo, Qiongmei Ji, Pingchang Yang, Zhigang Liu: Exploration of the effect of probiotics supplementation on intestinal microbiota of food allergic mice. Am J Transl Res 2017;9(2):376-385. (Abstract AJTR0035123, Full text, PDF).

Chunxia Zhou, Jie Bai, Chuan Jiang, Lincai Ye, Yanjun Pan, Haibo Zhang: Geranylgeranylacetone attenuates myocardium ischemic/reperfusion injury through HSP70 and Akt/GSK-3β/eNOS pathway. Am J Transl Res 2017;9(2):386-395. (Abstract AJTR0036151, Full text, PDF).

Hongbin Zhu, Gengyun Sun, Jiahui Dong, Liming Fei: The role of PRRX1 in the apoptosis of A549 cells induced by cisplatin. Am J Transl Res 2017;9(2):396-402. (Abstract AJTR0038978, Full text, PDF).

Jinxuan Hou, Hui Yang, Xin Huang, Xiaohua Leng, Fuxiang Zhou, Conghua Xie, Yunfeng Zhou, Yu Xu: N-WASP promotes invasion and migration of cervical cancer cells through regulating p38 MAPKs signaling pathway. Am J Transl Res 2017;9(2):403-415. (Abstract AJTR0040322, Full text, PDF).

Jianming He, Feng Wang, Fen Luo, Xuedan Chen, Xi Liang, Wenbin Jiang, Zhizhong Huang, Jiafan Lei, Fabo Shan, Xueqing Xu: Effects of long term low- and high-dose sodium arsenite exposure in human transitional cells. Am J Transl Res 2017;9(2):416-428. (Abstract AJTR0040587, Full text, PDF).

Shadan Li, Bin Liu, Qiunong Guan, Irina Chafeeva, Donald E Brooks, Christopher YC Nguan, Jayachandran N Kizhakkedathu, Caigan Du: Cold preservation with hyperbranched polyglycerol-based solution improves kidney functional recovery with less injury at reperfusion in rats. Am J Transl Res 2017;9(2):429-441. (Abstract AJTR0044779, Full text, PDF).

Ting Zhu, Longwei Qiao, Qian Wang, Rui Mi, Jinnan Chen, Yaojuan Lu, Junxia Gu, Qiping Zheng: T-box family of transcription factor-TBX5, insights in development and disease. Am J Transl Res 2017;9(2):442-453. (Abstract AJTR0039839, Full text, PDF).

Zheng Zhang, Qi He, Ying Tao, Juan Guo, Feng Xu, Ling-Yun Wu, You-Shan Zhao, Dong Wu, Li-Yu Zhou, Ji-Ying Su, Lu-Xi Song, Chao Xiao, Xiao Li, Chun-Kang Chang: Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes. Am J Transl Res 2017;9(2):454-465. (Abstract AJTR0042797, Full text, PDF).

Yang Lin, Yang Jin, Tianmin Xu, Shunqing Zhou, Manhua Cui: MicroRNA-215 targets NOB1 and inhibits growth and invasion of epithelial ovarian cancer. Am J Transl Res 2017;9(2):466-477. (Abstract AJTR0039615, Full text, PDF).

Guodong Xu, Guofeng Shao, Qiaoling Pan, Lebo Sun, Dawei Zheng, Minghui Li, Ni Li, Huoshun Shi, Yiming Ni: MicroRNA-9 regulates non-small cell lung cancer cell invasion and migration by targeting eukaryotic translation initiation factor 5A2. Am J Transl Res 2017;9(2):478-488. (Abstract AJTR0044311, Full text, PDF).

Yue Lv, Lihong Ge, Yuming Zhao: Effect and mechanism of SHED on ulcer wound healing in Sprague-Dawley rat models with diabetic ulcer. Am J Transl Res 2017;9(2):489-498. (Abstract AJTR0038629, Full text, PDF).

Hongli Yu, Yeqing Chen, Hao Wu, Kuilong Wang, Liping Liu, Xingde Zhang: Synthesis of huaicarbon A/B and their activating effects on platelet glycoprotein VI receptor to mediate collagen-induced platelet aggregation. Am J Transl Res 2017;9(2):499-506. (Abstract AJTR0038327, Full text, PDF).

Si-Rui Ma, Liang Mao, Wei-Wei Deng, Yi-Cun Li, Lin-Lin Bu, Guang-Tao Yu, Wen-Feng Zhang, Zhi-Jun Sun: AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma. Am J Transl Res 2017;9(2):507-519. (Abstract AJTR0036398, Full text, PDF).

Bo Liu, Ting Sun, Gang Wu, Hui Shang-Guan, Zhao-Jin Jiang, Ji-Ren Zhang, Yan-Fang Zheng: MiR-15a suppresses hepatocarcinoma cell migration and invasion by directly targeting cMyb. Am J Transl Res 2017;9(2):520-532. (Abstract AJTR0040269, Full text, PDF).

Ouchen Wang, Fan Yang, Yehuan Liu, Lin Lv, Ruimin Ma, Chuanzhi Chen, Jiao Wang, Qiufan Tan, Yue Cheng, Erjie Xia, Yizuo Chen, Xiaohua Zhang: C-MYC-induced upregulation of lncRNA SNHG12 regulates cell proliferation, apoptosis and migration in triple-negative breast cancer. Am J Transl Res 2017;9(2):533-545. (Abstract AJTR0041944, Full text, PDF).

Xu Wu, Huan Lu, Lijuan Hu, Wankun Gong, Juan Wang, Cuiping Fu, Zilong Liu, Shanqun Li: Chronic intermittent hypoxia affects endogenous serotonergic inputs and expression of synaptic proteins in rat hypoglossal nucleus. Am J Transl Res 2017;9(2):546-557. (Abstract AJTR0042154, Full text, PDF).

Luuk C Otterspoor, Lokien X van Nunen, Tilaï T Rosalina, Marcel van’t Veer, Sjoerd Van Tuijl, Marco Stijnen, Marcel CM Rutten, Frans N van de Vosse, Nico HJ Pijls: Intracoronary hypothermia for acute myocardial infarction in the isolated beating pig heart. Am J Transl Res 2017;9(2):558-568. (Abstract AJTR0041965, Full text, PDF, Video S1).

Jianghua Yang, Dandan Zhu, Bowei Ju, Xiangying Jiang, Junping Hu: Hepatoprotective effects of Gentianella turkestanerum extracts on acute liver injury induced by carbon tetrachloride in mice. Am J Transl Res 2017;9(2):569-579. (Abstract AJTR0036841, Full text, PDF).

Matteo Figini, Xifu Wang, Tianchu Lyu, Zhanliang Su, Daniele Procissi, Vahid Yaghmai, Andrew C Larson, Zhuoli Zhang: Preclinical and clinical evaluation of the liver tumor irreversible electroporation by magnetic resonance imaging. Am J Transl Res 2017;9(2):580-590. (Abstract AJTR0037958, Full text, PDF).

Yize Li, Huayu Zhu, Xu Wei, Heng Li, Zhicao Yu, Hongmei Zhang, Wenchao Liu: LPS induces HUVEC angiogenesis in vitro through miR-146a-mediated TGF-β1 inhibition. Am J Transl Res 2017;9(2):591-600. (Abstract AJTR0037495, Full text, PDF).

Aditya N Bade, Howard E Gendelman, Michael D Boska, Yutong Liu: MEMRI is a biomarker defining nicotine-specific neuronal responses in subregions of the rodent brain. Am J Transl Res 2017;9(2):601-610. (Abstract AJTR0039779, Full text, PDF).

Hong-Pei Ji, Yu Xiong, En-Dong Zhang, Wei-Tao Song, Zhao-Lin Gao, Fei Yao, Hong Sun, Rong-Rong Zhou, Xiao-Bo Xia: Which has more stem-cell characteristics: Müller cells or Müller cells derived from in vivo culture in neurospheres? Am J Transl Res 2017;9(2):611-619. (Abstract AJTR0036071, Full text, PDF).

Li Lin, Weihua Zhao, Bo Sun, Xinyu Wang, Qiao Liu: Overexpression of TRIM24 is correlated with the progression of human cervical cancer. Am J Transl Res 2017;9(2):620-628. (Abstract AJTR0037414, Full text, PDF).

Xinqi Zhang, Hua Shi, Yuanlin Wang, Jianxin Hu, Zhaolin Sun, Shuxiong Xu: Down-regulation of hsa-miR-148b inhibits vascular smooth muscle cells proliferation and migration by directly targeting HSP90 in atherosclerosis. Am J Transl Res 2017;9(2):629-637. (Abstract AJTR0038411, Full text, PDF).

Yi Han, Chongyu Su, Daping Yu, Shijie Zhou, Xiaoyun Song, Shuku Liu, Ming Qin, Yunsong Li, Ning Xiao, Xiaoqing Cao, Kang Shi, Xu Cheng, Zhidong Liu: Cholecystokinin attenuates radiation-induced lung cancer cell apoptosis by modulating p53 gene transcription. Am J Transl Res 2017;9(2):638-646. (Abstract AJTR0043097, Full text, PDF).

Ming Bai, Mingzi Zhang, Fei Long, Nanze Yu, Ang Zeng, Xiaojun Wang: MiR-217 promotes cutaneous squamous cell carcinoma progression by targeting PTRF. Am J Transl Res 2017;9(2):647-655. (Abstract AJTR0043286, Full text, PDF).

Yun-Feng Di, De-Cai Li, Yan-Qing Shen, Chun-Lei Wang, Da-Yong Zhang, An-Quan Shang, Teng Hu: MiR-146b protects cardiomyocytes injury in myocardial ischemia/reperfusion by targeting Smad4. Am J Transl Res 2017;9(2):656-663. (Abstract AJTR0027143, Full text, PDF).

Yuya Tanaka, Tohru Hosoyama, Akihito Mikamo, Hiroshi Kurazumi, Arata Nishimoto, Koji Ueno, Bungo Shirasawa, Kimikazu Hamano: Hypoxic preconditioning of human cardiosphere-derived cell sheets enhances cellular functions via activation of the PI3K/Akt/mTOR/HIF-1α pathway. Am J Transl Res 2017;9(2):664-673. (Abstract AJTR0040523, Full text, PDF).

Shiguang Cao, Ruiying Sun, Wei Wang, Xia Meng, Yuping Zhang, Na Zhang, Shuanying Yang: RNA helicase DHX9 may be a therapeutic target in lung cancer and inhibited by enoxacin. Am J Transl Res 2017;9(2):674-682. (Abstract AJTR0035424, Full text, PDF).

Li Yang, Wei Zhao, Ping Wei, Wenshu Zuo, Shouhui Zhu: Tumor suppressor p53 induces miR-15a processing to inhibit neuronal apoptosis inhibitory protein (NAIP) in the apoptotic response DNA damage in breast cancer cell. Am J Transl Res 2017;9(2):683-691. (Abstract AJTR0041446, Full text, PDF).

Qingjun Pan, Jun Cai, Yanxia Peng, Haiyan Xiao, Lifang Zhang, Jinying Chen, Huafeng Liu: Protective effect of a novel antibody against TLR2 on zymosan-induced acute peritonitis in NF-κB transgenic mice. Am J Transl Res 2017;9(2):692-699. (Abstract AJTR0039247, Full text, PDF).

Yi Yang, Bai-Jun Cheng, Hong Jian, Zhi-Wei Chen, Yi Zhao, Yong-Feng Yu, Zi-Ming Li, Mei-Lin Liao, Shun Lu: XBP1-LOX Axis is critical in ER stress-induced growth of lung adenocarcinoma in 3D culture. Am J Transl Res 2017;9(2):700-707. (Abstract AJTR0039059, Full text, PDF).

Ming-Peng Zhang, Wei-San Zhang, Jin Tan, Ming-Hui Zhao, Lin-Juan Lian, Jie Cai: Poly r(C) binding protein (PCBP) 1 expression is regulated at the post-translation level in thyroid carcinoma. Am J Transl Res 2017;9(2):708-714. (Abstract AJTR0039612, Full text, PDF).

Chang-Ping Li, Hong-Jue Li, Jiao Nie, Xia Chen, Xian Zhou: Mutation of miR-21 targets endogenous lipoprotein receptor-related protein 6 and nonalcoholic fatty liver disease. Am J Transl Res 2017;9(2):715-721. (Abstract AJTR0031493, Full text, PDF).

Lei Zhang, Yi Wang, Nuruliarizki Shinta Pandupuspitasari, Guorao Wu, Xudong Xiang, Quan Gong, Weining Xiong, Cong-Yi Wang, Ping Yang, Boxu Ren: Endoplasmic reticulum stress, a new wrestler, in the pathogenesis of idiopathic pulmonary fibrosis. Am J Transl Res 2017;9(2):722-735. (Abstract AJTR0048243, Full text, PDF).

Wen-Xing Li, Fei Qi, Jia-Qian Liu, Gong-Hua Li, Shao-Xing Dai, Tao Zhang, Fei Cheng, Dahai Liu, Song Guo Zheng: Different impairment of immune and inflammation functions in short and long-term after ischemic stroke. Am J Transl Res 2017;9(2):736-745. (Abstract AJTR0042441, Full text, PDF).

Xinge Shi, Hui Ye, Xuedong Yao, Yanzheng Gao: The involvement and possible mechanism of NR4A1 in chondrocyte apoptosis during osteoarthritis. Am J Transl Res 2017;9(2):746-754. (Abstract AJTR0042939, Full text, PDF).

Yan Zhao, Qingfeng Meng, Xu Gao, Lihua Zhang, Lixin An: Down-regulation of mediator complex subunit 19 (Med19) induces apoptosis in human laryngocarcinoma HEp2 cells in an Apaf-1-dependent pathway. Am J Transl Res 2017;9(2):755-761. (Abstract AJTR0038848, Full text, PDF).

Zhisheng Ji, Zhenbin Cai, Jifeng Zhang, Nannuan Liu, Jing Chen, Minghui Tan, Hongsheng Lin, Guoqing Guo: Rho kinase regulates neurite outgrowth of hippocampal neurons via calcium dependent cytoskeleton regulation. Am J Transl Res 2017;9(2):762-773. (Abstract AJTR0040942, Full text, PDF).

Amr M Mohamed, Bassem A Refaat, Adel G El-Shemi, Osama A Kensara, Jawwad Ahmad, Shakir Idris: Thymoquinone potentiates chemoprotective effect of Vitamin D3 against colon cancer: a pre-clinical finding. Am J Transl Res 2017;9(2):774-790. (Abstract AJTR0040368, Full text, PDF).

Xin-Ke Chen, Li-Juan Ouyang, Zheng-Qin Yin, Yuan-You Xia, Xiu-Rong Chen, Hui Shi, Yan Xiong, Lian-Hong Pi: Effects of microRNA-29a on retinopathy of prematurity by targeting AGT in a mouse model. Am J Transl Res 2017;9(2):791-801. (Abstract AJTR0046897, Full text, PDF).

Zheng Jin, Ying Yu, Ri-Hua Jin, Yu-Bo Wang, Hai-Yang Xu: Effect of granatin B on the glioma cancer by inducing apoptosis: Am J Transl Res. 2016;8(9):3970-3975. Am J Transl Res 2017;9(2):802. (Abstract AJTR0043953, Full text, PDF).

Jun Ouyang, Xiaohui Pan, Hui Lin, Zecheng Hu, Ping Xiao, Haobin Hu: GKN2 increases apoptosis, reduces the proliferation and invasion ability of gastric cancer cells through down-regulating the JAK/STAT signaling pathway. Am J Transl Res 2017;9(2):803-811. (Abstract AJTR0037566, Full text, PDF).

Jiao Liu, Chuang Chen, Guang Li, Dechang Chen, Qingshan Zhou: Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis. Am J Transl Res 2017;9(2):812-822. (Abstract AJTR0043496, Full text, PDF).